Generic equivalent of CARBOPLATIN
6 SKUs available · Available to order · NABP accredited · DSCSA compliant
Carboplatin is the generic equivalent of the brand-name drug CARBOPLATIN. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Carboplatin through Premier Pharma with same-day fulfillment on in-stock SKUs.
INDICATIONS Initial Treatment of Advanced Ovarian Carcinoma Carboplatin injection is indicated for the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of carboplatin and cyclophosphamide. Two randomized controlled studies conducted by the NCIC and SWOG with carboplatin versus cisplatin, both in combination with cyclophosphamide, have demonstrated equivalent overall survival between the two groups (see CLINICAL STUDIES ). There is limited statistical power to demonstrate equivalence in overall pathologic complete response rates and long-term survival (≥ 3 years) because of the…
WARNINGS Bone marrow suppression (leukopenia, neutropenia, and thrombocytopenia) is dose-dependent and is also the dose-limiting toxicity. Peripheral blood counts should be frequently monitored during carboplatin injection treatment and, when appropriate, until recovery is achieved. Median nadir occurs at day 21 in patients receiving single agent carboplatin. In general, single intermittent courses of carboplatin should not be repeated until leukocyte, neutrophil, and platelet counts have recove…
ADVERSE REACTIONS For a comparison of toxicities when carboplatin or cisplatin was given in combination with cyclophosphamide, see CLINICAL STUDIES, Use with Cyclophosphamide for Initial Treatment of Ovarian Cancer, Comparative Toxicity . ADVERSE EXPERIENCES IN PATIENTS WITH OVARIAN CANCER First Line Combination Therapy Use with Cyclophosphamide for Initial Treatment of Ovarian Cancer: Data are based on the experience of 393 patients with ovarian cancer (regardless of baseline status) who receiv…
Drug Interactions The renal effects of nephrotoxic compounds may be potentiated by carboplatin.
DOSAGE AND ADMINISTRATION NOTE: Aluminum reacts with carboplatin causing precipitate formation and loss of potency, therefore, needles or intravenous sets containing aluminum parts that may come in contact with the drug must not be used for the preparation or administration of carboplatin injection. Single Agent Therapy Carboplatin injection, as a single agent, has been shown to be effective in patients with recurrent ovarian carcinoma at a dosage of 360 mg/m 2 intravenously on day 1 every 4 wee…
Source: FDA. For professional use only. Not a substitute for prescribing information.
Premier Pharma stocks 6 Carboplatin SKUs — 0 currently in stock — available to licensed pharmacies, clinics, doctor's offices, and veterinary practices. Carboplatin is the generic equivalent of CARBOPLATIN. Create a free account to see live wholesale pricing and place orders with same-day fulfillment for in-stock items.
Premier Pharma carries Carboplatin in 10 mg/mL, 450 mg/45mL, 600 mg/60mL and INJECTION, INJECTION, SOLUTION.
Carboplatin carries an FDA Orange Book TE code of AP. Therapeutically equivalent — injectable aqueous solution. Always verify substitution with the current Orange Book before dispensing.
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