Generic equivalent of Diltiazem Hydrochloride, Diltiazem Hydrochloride EXTENDED RELEASE
9 SKUs available · Available to order · NABP accredited · DSCSA compliant
Diltiazem hydrochloride is the generic equivalent of the brand-name drug Diltiazem Hydrochloride, Diltiazem Hydrochloride EXTENDED RELEASE. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Diltiazem hydrochloride through Premier Pharma with same-day fulfillment on in-stock SKUs.
INDICATIONS AND USAGE Diltiazem Hydrochloride Extended-release Capsules, USP are indicated for the treatment of hypertension. Diltiazem hydrochloride may be used alone or in combination with other antihypertensive medications, such as diuretics. Diltiazem Hydrochloride Extended-release Capsules, USP are indicated for the management of chronic stable angina.
WARNINGS Cardiac Conduction: Diltiazem hydrochloride prolongs AV node refractory periods without significantly prolonging sinus node recovery time, except in patients with sick sinus syndrome. This effect may rarely result in abnormally slow heart rates (particularly in patients with sick sinus syndrome) or second, or third degree AV block (22 of 10,119 patients, or 0.2%); 41% of these 22 patients were receiving concomitant β-adrenoceptor antagonists versus 17% of the total group. Concomitant us…
ADVERSE REACTIONS Serious adverse reactions to diltiazem hydrochloride have been rare in studies with other formulations, as well as with diltiazem hydrochloride extended-release capsules. It should be recognized, however, that patients with impaired ventricular function and cardiac conduction abnormalities have usually been excluded from these studies. Hypertension: The most common adverse events (frequency ≥1%) in placebo-controlled, clinical hypertension studies with diltiazem hydrochloride e…
Drug Interactions: Due to the potential for additive effects, caution and careful titration are warranted in patients receiving diltiazem hydrochloride concomitantly with any agents known to affect cardiac contractility and/or conduction. (See WARNINGS .) Pharmacologic studies indicate that there may be additive effects in prolonging AV conduction when using beta-blockers or digitalis concomitantly with diltiazem hydrochloride. (See WARNINGS .) As with all drugs, care should be exercised when tr…
DOSAGE AND ADMINISTRATION Hypertensive or anginal patients who are treated with other formulations of diltiazem can safely be switched to diltiazem hydrochloride extended-release capsules at the nearest equivalent total daily dose. Subsequent titration to higher or lower doses may, however, be necessary and should be initiated as clinically indicated. Studies have shown a slight increase in the rate of absorption of diltiazem hydrochloride extended-release capsules when ingested with a high-fat…
Information for Patients: Diltiazem Hydrochloride Extended-release Capsules should be taken on an empty stomach. Patients should be cautioned that the diltiazem hydrochloride extended-release capsules should not be opened, chewed or crushed, and should be swallowed whole.
Source: FDA. For professional use only. Not a substitute for prescribing information.
Premier Pharma stocks 9 Diltiazem hydrochloride SKUs — 0 currently in stock — available to licensed pharmacies, clinics, doctor's offices, and veterinary practices. Diltiazem hydrochloride is the generic equivalent of Diltiazem Hydrochloride. Create a free account to see live wholesale pricing and place orders with same-day fulfillment for in-stock items.
Premier Pharma carries Diltiazem hydrochloride in 120 mg/1, 180 mg/1, 240 mg/1 and CAPSULE, EXTENDED RELEASE.
Diltiazem hydrochloride carries an FDA Orange Book TE code of AB2. Therapeutically equivalent — meets FDA bioequivalence requirements; may be substituted for the reference listed drug. Always verify substitution with the current Orange Book before dispensing.
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