Generic equivalent of Flumazenil
2 SKUs available · Available to order · NABP accredited · DSCSA compliant
Flumazenil is the generic equivalent of the brand-name drug Flumazenil. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Flumazenil through Premier Pharma with same-day fulfillment on in-stock SKUs.
INDICATIONS AND USAGE Adult Patients: Flumazenil injection is indicated for the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures, and for the management of benzodiazepine overdose. Pediatric Patients (aged 1 to 17): Flumazenil injection is indicated for the reversal of conscious sedation induced with benzodiazepines (see PRECAUTIONS: Pediatric Use ).
WARNINGS THE USE OF FLUMAZENIL HAS BEEN ASSOCIATED WITH THE OCCURRENCE OF SEIZURES. THESE ARE MOST FREQUENT IN PATIENTS WHO HAVE BEEN ON BENZODIAZEPINES FOR LONG-TERM SEDATION OR IN OVERDOSE CASES WHERE PATIENTS ARE SHOWING SIGNS OF SERIOUS CYCLIC ANTI-DEPRESSANT OVERDOSE. PRACTITIONERS SHOULD INDIVIDUALIZE THE DOSAGE OF FLUMAZENIL AND BE PREPARED TO MANAGE SEIZURES. Risk of Seizures: The reversal of benzodiazepine effects may be associated with the onset of seizures in certain high-risk populat…
ADVERSE REACTIONS Serious Adverse Reactions: Deaths have occurred in patients who received flumazenil in a variety of clinical settings. The majority of deaths occurred in patients with serious underlying disease or in patients who had ingested large amounts of non-benzodiazepine drugs (usually cyclic antidepressants), as part of an overdose. Serious adverse events have occurred in all clinical settings, and convulsions are the most common serious adverse events reported. Flumazenil administrati…
Drug Interactions: Interaction with central nervous system depressants other than benzodiazepines has not been specifically studied; however, no deleterious interactions were seen when flumazenil was administered after narcotics, inhalational anesthetics, muscle relaxants and muscle relaxant antagonists administered in conjunction with sedation or anesthesia. Particular caution is necessary when using flumazenil in cases of mixed drug overdosage since the toxic effects (such as convulsions and c…
DOSAGE AND ADMINISTRATION Flumazenil injection, USP is recommended for intravenous use only. It is compatible with 5% dextrose in water, lactated Ringer’s and normal saline solutions. If flumazenil injection is drawn into a syringe or mixed with any of these solutions, it should be discarded after 24 hours. For optimum sterility, flumazenil injection should remain in the vial until just before use. As with all parenteral drug products, flumazenil injection should be inspected visually for partic…
Information for Patients: Flumazenil does not consistently reverse amnesia. Patients cannot be expected to remember information told to them in the postprocedure period and instructions given to patients should be reinforced in writing or given to a responsible family member. Physicians are advised to discuss with patients or their guardians, both before surgery and at discharge, that although the patient may feel alert at the time of discharge, the effects of the benzodiazepine (e.g., sedation) may recur. As a result, the patient should be instructed, preferably in writing, that their memory…
Source: FDA. For professional use only. Not a substitute for prescribing information.
| Name | Status |
|---|---|
| FLUMAZENIL INJ 0.1MG/ML 10ML/VL Baxter Healthcare Corporation | 2-Day |
| FLUMAZENIL INJ 0.1MG/ML 5ML/VL Baxter Healthcare Corporation | 2-Day |
Premier Pharma stocks 2 Flumazenil SKUs — 0 currently in stock — available to licensed pharmacies, clinics, doctor's offices, and veterinary practices. Flumazenil is the generic equivalent of Flumazenil. Create a free account to see live wholesale pricing and place orders with same-day fulfillment for in-stock items.
Premier Pharma carries Flumazenil in .1 mg/mL and INJECTION. Available from manufacturers including Baxter Healthcare Corporation.
Flumazenil carries an FDA Orange Book TE code of AP. Therapeutically equivalent — injectable aqueous solution. Always verify substitution with the current Orange Book before dispensing.
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