Torsemide is the generic equivalent of the brand-name drug Torsemide. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Torsemide through Premier Pharma with same-day fulfillment on in-stock SKUs.
FDA Drug Information
Indications & Usage
1 INDICATIONS & USAGE Torsemide tablets are a loop diuretic indicated for: • the treatment of edema associated with heart failure, renal disease or hepatic disease. (1.1) • the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. (1.2) 1.1 Edema Torsemide tablets are indicated for the treatment of edema associated with heart failure, renal disease or hepatic disease. 1.2 Hypertension Torsemide tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, prim…
Adverse Reactions
6 ADVERSE REACTIONS The following risks are discussed in more detail in others sections: • Hypotension and Worsening Renal Function [see Warnings and Precautions (5.1)] • Electrolyte and Metabolic Abnormalities [see Warnings and Precautions (5.2)] • Ototoxicity [see Warnings and Precautions (5.3)] The most common adverse reaction is excessive urination (6.7%). (6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Hetero Labs Limited at 1-866-495-1995 or FDA at 1-800-FDA-1088 or www.fda.gov/medwa…
Drug Interactions
7 DRUG INTERACTIONS • Non-steroidal anti-inflammatory drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects; risk of renal impairment. (7.1) • CYP2C9: Concomitant use with CYP2C9 inhibitors can decrease torsemide clearance. Torsemide may affect the efficacy and safety of sensitive CYP2C9 substrates or of substrates with a narrow therapeutic range, such as warfarin or phenytoin. (7.2) • Cholestyramine: Decreased exposure of torsemide. (7.3) • Organic anion drugs: may decreas…
Dosage & Administration
2 DOSAGE & ADMINISTRATION Edema associated with: • Heart failure: Initial dose is 10 or 20 mg once daily. Titrate by factors of two; doses above 200 mg have not been studied. (2.1) • Chronic Renal Failure: Initial dose is 20 mg once daily. Titrate by factors of two; doses above 200 mg have not been studied. (2.1) • Hepatic Cirrhosis: Initial dose is 5 or 10 mg once daily. Titrate by factors of two; doses above 40 mg have not been studied. (2.1) Hypertension: • The recommended initial dose is 5 m…
Patient Counseling Information
17 PATIENT COUNSELING INFORMATION Symptomatic Hypotension: Advise patients receiving torsemide tablets that lightheadedness can occur, especially during the first days of therapy, and that it should be reported to the prescribing physician. The patients should be told that if syncope occurs, torsemide should be discontinued until the physician has been consulted. All patients should be cautioned that inadequate fluid intake, excessive perspiration, diarrhea, or vomiting can lead to an excessive fall in blood pressure, with the same consequences of lightheadedness and possible syncope [see Warn…
Source: FDA. For professional use only. Not a substitute for prescribing information.
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