Lisinopril is the generic equivalent of the brand-name drug LISINOPRIL. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Lisinopril through Premier Pharma with same-day fulfillment on in-stock SKUs.
FDA Drug Information
Indications & Usage
1 INDICATIONS AND USAGE Lisinopril is an angiotensin converting enzyme (ACE) inhibitor indicated for: • Treatment of hypertension in adults and pediatric patients 6 years of age and older (1.1) • Adjunct therapy for heart failure (1.2) • Treatment of Acute Myocardial Infarction (1.3) 1.1 Hypertension Lisinopril tablets, USP, are indicated for the treatment of hypertension in adult patients and pediatric patients 6 years of age and older to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of ph…
Adverse Reactions
6 ADVERSE REACTIONS Common adverse reactions (events 2% greater than placebo) by use: • Hypertension: headache, dizziness and cough (6.1) • Heart Failure: hypotension and chest pain (6.1) • Acute Myocardial Infarction: hypotension (6.1) To report SUSPECTED ADVERSE REACTIONS, contact Solco Healthcare US, LLC at 1-866-257-2597 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rate…
Drug Interactions
7 DRUG INTERACTIONS • Diuretics: Excessive drop in blood pressure (7.1) • NSAIDS: Increased risk of renal impairment and loss of antihypertensive efficacy (7.3) • Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension and hyperkalemia (7.4) • Lithium: Symptoms of lithium toxicity (7.5) • Gold: Nitritoid reactions have been reported (7.6) • Concomitant mTOR inhibitor or neprilysin inhibitor use may increase angioedema risk ( 7.7 , 7.8 ) 7.1 Diuretics Init…
Dosage & Administration
2 DOSAGE AND ADMINISTRATION • Hypertension: Initial adult dose is 10 mg once daily. Titrate up to 40 mg daily based on blood pressure response. Initiate patients on diuretics at 5 mg once daily (2.1) • Pediatric patients with glomerular filtration rate > 30 mL/min/1.73 m 2 : Initial dose in patients 6 years of age and older is 0.07 mg per kg (up to 5 mg total) once daily (2.1) • Heart Failure: Initiate with 5 mg once daily. Increase dose as tolerated to 40 mg daily (2.2) • Acute Myocardial Infar…
Patient Counseling Information
17 PATIENT COUNSELING INFORMATION NOTE: This information is intended to aid in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects. Pregnancy: Advise pregnant women and females of reproductive potential of the potential risk to a fetus. Advise females of reproductive potential to notify their healthcare provider with a known or suspected pregnancy [see Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ]. Angioedema: Angioedema, including laryngeal edema may occur at any time during treatment with angiotensin conve…
Source: FDA. For professional use only. Not a substitute for prescribing information.
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