Methylprednisolone is the generic equivalent of the brand-name drug METHYLPREDNISOLONE. Licensed pharmacies, clinics, doctor's offices, and veterinary practices can source wholesale Methylprednisolone through Premier Pharma with same-day fulfillment on in-stock SKUs.
FDA Drug Information
Indications & Usage
INDICATIONS AND USAGE Methylprednisolone Tablets are indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance). Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require…
Important Warnings
WARNINGS In patients on corticosteroid therapy subjected to unusual stress, increased dosage of rapidly acting corticosteroids before, during, and after the stressful situation is indicated. Immunosuppression and Increased Risk of Infection Corticosteroids, including Methylprednisolone Tablets, suppress the immune system and increase the risk of infection with any pathogen, including viral, bacterial, fungal, protozoan, or helminthic pathogens. Corticosteroids can: • Reduce resistance to new inf…
Adverse Reactions
ADVERSE REACTIONS Fluid and Electrolyte Disturbances ▪ Sodium retention ▪ Congestive heart failure in susceptible patients ▪ Hypertension ▪ Fluid retention ▪ Potassium loss ▪ Hypokalemic alkalosis Musculoskeletal ▪ Muscle weakness ▪ Loss of muscle mass ▪ Steroid myopathy ▪ Osteoporosis ▪ Tendon rupture, particularly of the Achilles tendon ▪ Vertebral compression fractures ▪ Aseptic necrosis of femoral and humeral heads ▪ Pathologic fracture of long bones Gastrointestinal ▪ Peptic ulcer with poss…
Drug Interactions
DRUG INTERACTIONS The pharmacokinetic interactions listed below are potentially clinically important. Mutual inhibition of metabolism occurs with concurrent use of cyclosporin and methylprednisolone; therefore, it is possible that adverse events associated with the individual use of either drug may be more apt to occur. Convulsions have been reported with concurrent use of methylprednisolone and cyclosporin. Drugs that induce hepatic enzymes such as phenobarbital, phenytoin and rifampin may incr…
Dosage & Administration
DOSAGE AND ADMINISTRATION The initial dosage of Methylprednisolone Tablets may vary from 4 mg to 48 mg of methylprednisolone per day depending on the specific disease entity being treated. In situations of less severity lower doses will generally suffice while in selected patients higher initial doses may be required. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If after a reasonable period of time there is a lack of satisfactory clinical response,…
Patient Counseling Information
Information for the Patient Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chickenpox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Source: FDA. For professional use only. Not a substitute for prescribing information.
Ready to order Methylprednisolone at wholesale?
Create a free Premier Pharma account to unlock live wholesale pricing, place orders, and track shipments — approval typically takes minutes for licensed pharmacies, clinics, doctor's offices, and veterinary practices.